MEA Services


Directed differentiation of iPSCs
to neural, cardiac, immune
and other cell types

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Are you looking to derive iPS cells from your specific donor samples?

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Are you studying gene function or modeling a disease in a dish?

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Are you looking for custom iPSC-derived cells?

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What we offer


We specialise in the supply of human cell culture systems and custom services for disease modeling and drug discovery

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Axol Bioscience has combined its extensive catalogue of iPSC-derived cell-types, its wealth of experience working with these cells and over 20 years of in-house electrophysiology expertise with the market-leading Maestro Pro multiwell MEA system from Axion Biosystems to create an unrivalled offering of a bespoke electrophysiological assay service.

  • • 6-well, 24-well, 48-well and 96-well Formats

  • • Market-leading 132 parameter suite of electrophysiological options

  • • Waveform Characteristics, Electrode Activity, Bursting Behaviour, Network Properties, Oscillation, Synchrony

  • • Additional Impedance and Contractility Modes

  • • Label-free, Long-term, Continuous, Real-Time, Low Noise Recording

  • • Full Environmental Support

  • • Multiplexing Options


Multiple options


We offer multiple services for you to choose from:

We offer multiple services for you to choose from:

Neuronal - Host of services also featuring our in-house sensory cell lines
- Gold standard equipment and services including cardiotoxicity screening
- Our range of upcoming MEA services

 

Neuronal - Host of services also featuring our in-house sensory cell lines

• Neuronal Characteristics

• Disease Phenotyping

• Compound Screening

• Regional Variations

• Co-Culture

• Tri-Culture

• Quad-Culture

• Neurotoxicity Screening

• Seizurogenic Screening

• 3D Culture

• Side-by-Side Culture

• Neural Organoids

 

Cardiac - Gold standard equipment and services including cardiotoxicity screening

• Cardiac Characteristics

• Disease Phenotyping

• Compound Screening

• LEAP

• Contractility

• Impedance

• Inotrophic Compound Screening

• Cardiotoxicity Screening

o Acute Cardiotoxicity

- HERG block

- Off-target Effects

- Rise-time Changes

- Repolarization Effects

- Triangulation Detection

- Arrhythmia Detection

- Propagation Pattern Changes

- Conduction Velocity Changes

o Chronic Cardiotoxicity

- Cell Death

- Synctium Disruption

- Propagation Pattern Changes

- Conduction Velocity Changes

• Cardiac Pacing

• Co-Culture

• 3D Culture

• Cardiac Organoids

 

Coming Soon! - Our range of upcoming MEA services

Epithelial MEA Services

• Real-Time Tracking

• Impedance

• Blood-Brain Barrier Integrity

• Disease Models

• Cytotoxicity

• Scratch Assay, Wound Healing

• Proliferation, Migration and Invasion

• GCPR-function


Let us know


Do you have any questions about our services?

Axol Bioscience can also perform bespoke studies using calcium imaging, immunocytochemistry, cell morphology, cell survival, cell proliferation, PCR and Western Blot. Please contact our dedicated Services team for further information and any inquiries. Our custom services can be tailored to meet your experimental requirements, helping you to save time and resources.